iPTMnet Report for Q7Z5L9 (IRF2BP2)
Protein Information
UniProt AC / UniProt ID | Q7Z5L9 / I2BP2_HUMAN |
Protein Name | Interferon regulatory factor 2-binding protein 2 |
Gene Name | Name: IRF2BP2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z5L9 |
PRO Name | interferon regulatory factor 2-binding protein 2 (human) |
Definition | An interferon regulatory factor 2-binding protein 2 that is encoded in the genome of human. |
Short Label | hIRF2BP2 |
Category | organism-gene |
Q7Z5L9 (IRF2BP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S71 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
R109 | Methylation | score1 | PhosphoSitePlus | |||
R116 | Methylation | score1 | PhosphoSitePlus | |||
R125 | Methylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
T147 | Phosphorylation | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231, 17081983, 24275569 | ||
T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
S244 | Phosphorylation | score1 | PhosphoSitePlus | |||
S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
R291 | Methylation | score1 | PhosphoSitePlus | |||
S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
K303 | Ubiquitination | score1 | PhosphoSitePlus | |||
S318 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S323 | Phosphorylation | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 17081983, 21887377, ... | ||
S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
T404 | Phosphorylation | score1 | PhosphoSitePlus | |||
S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
S455 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S457 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
S460 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
S462 | Phosphorylation | score1 | PhosphoSitePlus | |||
S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
K539 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S175 | Phosphorylation | score0 | HPRD | 17081983, 19651622, 18669648, ... | ||
S240 | Phosphorylation | score0 | HPRD | 17081983, 18452278, 19651622, ... | ||
S242 | Phosphorylation | score0 | HPRD | 20166139 | ||
S272 | Phosphorylation | score0 | HPRD | 18452278 | ||
S318 | Phosphorylation | score0 | HPRD | 20166139 | ||
S323 | Phosphorylation | score0 | HPRD | 20166139 | ||
S360 | Phosphorylation | score0 | HPRD | 17081983, 20058876, 19664995, ... | ||
S381 | Phosphorylation | score0 | HPRD | 20068231 | ||
S396 | Phosphorylation | score0 | HPRD | 17081983 | ||
T404 | Phosphorylation | score0 | HPRD | 20068231 | ||
S406 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
T412 | Phosphorylation | score0 | HPRD | 18452278 | ||
T413 | Phosphorylation | score0 | HPRD | 18452278 | ||
S423 | Phosphorylation | score0 | HPRD | 18452278 | ||
S455 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S457 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S460 | Phosphorylation | score0 | HPRD | 19413330, 15302935, 19664995, ... | ||
S462 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S463 | Phosphorylation | score0 | HPRD | 19651622 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S175 | Phosphorylation | score0 | HPRD | 17081983, 19651622, 18669648, ... | ||
S240 | Phosphorylation | score0 | HPRD | 17081983, 18452278, 19651622, ... | ||
S242 | Phosphorylation | score0 | HPRD | 20166139 | ||
S272 | Phosphorylation | score0 | HPRD | 18452278 | ||
S318 | Phosphorylation | score0 | HPRD | 20166139 | ||
S323 | Phosphorylation | score0 | HPRD | 20166139 | ||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
S344 | Phosphorylation | score0 | HPRD | 17081983, 20058876, 19664995, ... | ||
S365 | Phosphorylation | score0 | HPRD | 20068231 | ||
S380 | Phosphorylation | score0 | HPRD | 17081983 | ||
T388 | Phosphorylation | score0 | HPRD | 20068231 | ||
S390 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
T396 | Phosphorylation | score0 | HPRD | 18452278 | ||
T397 | Phosphorylation | score0 | HPRD | 18452278 | ||
S407 | Phosphorylation | score0 | HPRD | 18452278 | ||
S439 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S441 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S444 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 19664995, ... | ||
S446 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S447 | Phosphorylation | score0 | HPRD | 19651622 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | D2 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S78 | P78 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S272 | G272 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S290 | R290 | Biomuta | DOID:2531 / hematologic cancer [ tcga ] | |
S318 | * | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
K327 | N327 | Biomuta | DOID:10534 / stomach cancer [ tcga ] | |
S399 | C399 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S455 | G455 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S457 | T457 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K539 | R539 | Biomuta | DOID:10534 / stomach cancer [ tcga ] |