iPTMnet Report for Q7Z591 (AKNA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z591 / AKNA_HUMAN
Protein Name Microtubule organization protein AKNA
Gene Name Name: AKNA
Synonyms:KIAA1968;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z591
DAG View
PRO Name microtubule organization protein AKNA (human)
Definition A microtubule organization protein AKNA that is encoded in the genome of human.
Short Label hAKNA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z591 (AKNA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus   UniProt 23186163
S151 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus   UniProt 23186163
R351 Methylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
T427 Phosphorylation PhosphoSitePlus
Y450 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus   UniProt 23186163
S507 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus   UniProt 19690332
T539 Phosphorylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
Y758 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus   UniProt 23186163
K769 Ubiquitination PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus   UniProt 23186163
K836 Ubiquitination PhosphoSitePlus
S839 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K841 Ubiquitination PhosphoSitePlus
S848 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S856 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus   UniProt 23186163
K902 Ubiquitination PhosphoSitePlus
T940 Phosphorylation PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
T982 Phosphorylation PhosphoSitePlus
T986 Phosphorylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus   UniProt 23186163
S999 Phosphorylation PhosphoSitePlus
S1010 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1030 Acetylation PhosphoSitePlus
K1030 Ubiquitination PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
S1123 Phosphorylation PhosphoSitePlus
S1129 Phosphorylation PhosphoSitePlus
K1134 Acetylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
S1159 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
S1161 Phosphorylation PhosphoSitePlus
S1170 Phosphorylation IEDB 30784271
S1172 Phosphorylation PhosphoSitePlus
S1179 Phosphorylation PhosphoSitePlus
K1186 Ubiquitination PhosphoSitePlus
Y1219 Phosphorylation PhosphoSitePlus
T1220 Phosphorylation PhosphoSitePlus
Y1224 Phosphorylation PhosphoSitePlus
S1228 Phosphorylation IEDB   PhosphoSitePlus   UniProt 35494241, 23186163
S1303 Phosphorylation PhosphoSitePlus
S1307 Phosphorylation PhosphoSitePlus
T1330 Phosphorylation IEDB 32387766
T1375 Phosphorylation IEDB 32387766
S1377 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1387 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1422 Phosphorylation PhosphoSitePlus
S1424 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1436 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T51 Phosphorylation HPRD 20058876
S52 Phosphorylation HPRD 20058876
S839 Phosphorylation HPRD 17081983
S848 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R9 H9 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S151 R151 Biomuta DOID:3571 / liver cancer [ cosmic ]
S159 I159 Biomuta DOID:1324 / lung cancer [ cosmic ]
S184 C184 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S187 F187 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T284 M284 Biomuta DOID:363 / uterine cancer [ icgc ]
S303 T303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R351 Q351 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T420 M420 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S770 F770 Biomuta DOID:1324 / lung cancer [ cosmic ]
K836 N836 Biomuta DOID:1324 / lung cancer [ cosmic ]
S839 Y839 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S975 F975 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S975 Y975 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ]
S997 I997 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1123 C1123 Biomuta DOID:363 / uterine cancer [ icgc ]
S1160 F1160 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1179 F1179 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1228 Y1228 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1303 F1303 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1303 P1303 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1307 G1307 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1307 I1307 Biomuta DOID:184 / bone cancer [ cosmic ]
T1330 I1330 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1375 P1375 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1422 L1422 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1424 L1424 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]