iPTMnet Report for Q7Z569 (BRAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z569 / BRAP_HUMAN
Protein Name BRCA1-associated protein
Gene Name Name: BRAP
Synonyms:RNF52;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z569
DAG View
PRO Name BRCA1-associated protein (human)
Definition A BRCA1-associated protein that is encoded in the genome of human.
Short Label hBRAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z569 (BRAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K38 Ubiquitination PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S52 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S79 Phosphorylation PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus   UniProt 23186163
T99 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S117 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S119 Phosphorylation PhosphoSitePlus   UniProt 21406692
K154 Ubiquitination PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
C234 Methylation IEDB 31844290
S286 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K458 Acetylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation HPRD 18669648
S97 Phosphorylation HPRD 20068231
S117 Phosphorylation HPRD 19413330, 18669648, 19664995
S119 Phosphorylation HPRD 19413330, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K38 N38 Biomuta DOID:363 / uterine cancer [ icgc ]
S43 L43 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
K85 I85 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S117 Y117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S117 F117 Biomuta [ cosmic ]
S119 F119 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S286 R286 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S289 I289 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T308 M308 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T352 M352 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T352 P352 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y389 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K444 Q444 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S570 L570 Biomuta DOID:9256 / colorectal cancer [ cosmic ]