iPTMnet Report for Q7Z4W1 (DCXR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z4W1 / DCXR_HUMAN
Protein Name L-xylulose reductase
Gene Name Name: DCXR
Synonyms:SDR20C1;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z4W1
DAG View
PRO Name L-xylulose reductase (human)
Definition An L-xylulose reductase that is encoded in the genome of human.
Short Label hDCXR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z4W1 (DCXR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 12665801, 22223895, ...25944712
K17 Acetylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
R21 Methylation PhosphoSitePlus   UniProt 24129315
T23 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus   UniProt 24275569
T67 Phosphorylation PhosphoSitePlus
R102 Methylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
S151 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T40 I40 Biomuta DOID:263 / kidney cancer [ cosmic ]
T180 R180 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K196 Q196 Biomuta DOID:4159 / skin cancer [ cosmic ]