iPTMnet Report for Q7Z4Q2 (HEATR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z4Q2 / HEAT3_HUMAN
Protein Name HEAT repeat-containing protein 3
Gene Name Name: HEATR3
Organism Homo sapiens (Human)

PRO ID PR:Q7Z4Q2
DAG View
PRO Name HEAT repeat-containing protein 3 (human)
Definition A HEAT repeat-containing protein 3 that is encoded in the genome of human.
Short Label hHEATR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z4Q2 (HEATR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus   UniProt 24275569
T17 Phosphorylation PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus   UniProt 23186163
S343 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T17 Phosphorylation HPRD 18452278
T300 Phosphorylation HPRD 20058876
S551 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T17 M17 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T125 P125 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T300 M300 Biomuta DOID:363 / uterine cancer [ icgc ]
S551 R551 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K631 N631 Biomuta DOID:9256 / colorectal cancer [ cosmic ]