iPTMnet Report for Q7Z4N2 (TRPM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z4N2 / TRPM1_HUMAN
Protein Name Transient receptor potential cation channel subfamily M member 1
Gene Name Name: TRPM1
Synonyms:LTRPC1,MLSN;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z4N2
DAG View
PRO Name transient receptor potential cation channel subfamily M member 1 (human)
Definition A transient receptor potential cation channel subfamily M member 1 that is encoded in the genome of human.
Short Label hTRPM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z4N2 (TRPM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y189 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K418 Acetylation PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
K425 Acetylation PhosphoSitePlus
K430 Acetylation PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
K435 Acetylation PhosphoSitePlus
K436 Acetylation PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S813 Phosphorylation PhosphoSitePlus
T818 Phosphorylation PhosphoSitePlus
K886 Ubiquitination PhosphoSitePlus
S995 Phosphorylation IEDB 35494241
Y1095 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
Y1257 Phosphorylation PhosphoSitePlus
Y1270 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation IEDB 32387766
T1376 Phosphorylation PhosphoSitePlus
K1436 Acetylation PhosphoSitePlus
K1447 Acetylation PhosphoSitePlus
T1542 Phosphorylation PhosphoSitePlus
K1590 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T423 Phosphorylation HPRD 17081983
T424 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T492 N492 Biomuta DOID:1324 / lung cancer [ cosmic ]
T492 I492 Biomuta DOID:4159 / skin cancer [ cosmic ]
S995 F995 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1303 F1303 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1447 N1447 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]