iPTMnet Report for Q7Z4L5 (TTC21B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z4L5 / TT21B_HUMAN
Protein Name Tetratricopeptide repeat protein 21B
Gene Name Name: TTC21B
Synonyms:IFT139;ORFNames:Nbla10696;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z4L5
DAG View
PRO Name tetratricopeptide repeat protein 21B (human)
Definition A tetratricopeptide repeat protein 21B that is encoded in the genome of human.
Short Label hTTC21B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z4L5 (TTC21B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S95 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K109 Acetylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
K761 Ubiquitination PhosphoSitePlus
C792 Methylation IEDB 31844290
K846 Ubiquitination PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
K892 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
Y900 Phosphorylation PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
K905 Ubiquitination PhosphoSitePlus
C937 Methylation IEDB 31844290
K1020 Ubiquitination PhosphoSitePlus
Y1061 Phosphorylation PhosphoSitePlus
K1106 Ubiquitination PhosphoSitePlus
K1134 Ubiquitination PhosphoSitePlus
K1136 Ubiquitination PhosphoSitePlus
K1185 Ubiquitination PhosphoSitePlus
K1212 Ubiquitination PhosphoSitePlus
Y1213 Phosphorylation PhosphoSitePlus
K1221 Ubiquitination PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
K1243 Acetylation PhosphoSitePlus
K1278 Ubiquitination PhosphoSitePlus
C1289 Methylation IEDB 31844290
K1309 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T349 A349 Biomuta DOID:3571 / liver cancer [ cosmic ]
K905 Q905 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1213 F1213 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1229 F1229 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1243 N1243 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1243 * Biomuta DOID:1324 / lung cancer [ cosmic ]
C1289 Y1289 Biomuta DOID:363 / uterine cancer [ cosmic ]
C1289 S1289 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]