iPTMnet Report for Q7Z4H3 (HDDC2)
Protein Information
| UniProt AC / UniProt ID | Q7Z4H3 / HDDC2_HUMAN |
| Protein Name | 5'-deoxynucleotidase HDDC2 |
| Gene Name | Name: HDDC2 Synonyms:C6orf74,NS5ATP2;ORFNames:CGI-130; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z4H3 |
| PRO Name | 5'-deoxynucleotidase HDDC2 (human) |
| Definition | A 5'-deoxynucleotidase HDDC2 that is encoded in the genome of human. |
| Short Label | hHDDC2 |
| Category | organism-gene |
DAG ViewQ7Z4H3 (HDDC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| S3 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S5 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C70 | Methylation | score1 | IEDB | 31844290 | ||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K174 | Q174 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S204 | F204 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
