iPTMnet Report for Q7Z494 (NPHP3)
Protein Information
| UniProt AC / UniProt ID | Q7Z494 / NPHP3_HUMAN |
| Protein Name | Nephrocystin-3 |
| Gene Name | Name: NPHP3 Synonyms:KIAA2000; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z494 |
| PRO Name | nephrocystin-3 (human) |
| Definition | A nephrocystin-3 that is encoded in the genome of human. |
| Short Label | hNPHP3 |
| Category | organism-gene |
DAG ViewQ7Z494 (NPHP3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score2 | UniProt | 22085962 | ||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R47 | Methylation | score1 | PhosphoSitePlus | |||
| S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S758 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S987 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1008 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1039 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1095 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1320 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S73 | G73 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T1220 | A1220 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
