iPTMnet Report for Q7Z460 (CLASP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z460 / CLAP1_HUMAN
Protein Name CLIP-associating protein 1
Gene Name Name: CLASP1
Synonyms:KIAA0622,MAST1;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z460
DAG View
PRO Name CLIP-associating protein 1 (human)
Definition A CLIP-associating protein 1 that is encoded in the genome of human.
Short Label hCLASP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z460 (CLASP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C173 Methylation IEDB 31844290
S214 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus   UniProt 23186163
S254 Phosphorylation PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus   UniProt 23186163
S552 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus   UniProt 23186163
S559 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
S562 Phosphorylation PhosphoSitePlus
S568 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
S572 Phosphorylation PhosphoSitePlus
T574 O-Glycosylation GlyGen 23301498, 30379171, 34725712, ...30059200, 35254053, 34019948
T574 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
S579 O-Glycosylation GlyGen 23301498, 30379171, 34725712, ...30059200, 35254053, 34019948
T586 Phosphorylation PhosphoSitePlus
S588 O-Glycosylation GlyGen 23301498, 30379171, 34725712, ...30059200, 35254053, 34019948
S588 Phosphorylation PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
S600 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...19690332
S609 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S612 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
Y634 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus   UniProt 23186163
T642 Phosphorylation PhosphoSitePlus
S646 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 19690332, 20068231
S647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S649 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T651 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S655 Phosphorylation PhosphoSitePlus
T656 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
R660 Methylation PhosphoSitePlus
R662 Methylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus   UniProt 21406692
S686 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S687 Phosphorylation PhosphoSitePlus
S688 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S695 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y697 Phosphorylation PhosphoSitePlus
T701 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus   UniProt 23186163
R706 Methylation PhosphoSitePlus
T711 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S713 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S714 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S723 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
T730 O-Glycosylation GlyGen 23301498, 30379171, 34725712, ...30059200, 35254053, 34019948
T730 Phosphorylation PhosphoSitePlus
S731 Phosphorylation IEDB   PhosphoSitePlus 27920218
S740 Phosphorylation PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
T764 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus   UniProt 23186163
S795 Phosphorylation PhosphoSitePlus
T796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T798 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S823 Phosphorylation PhosphoSitePlus   UniProt 23186163
S829 Phosphorylation PhosphoSitePlus
C835 S-Nitrosylation dbSNO 26338901
S836 Phosphorylation PhosphoSitePlus
R843 Methylation PhosphoSitePlus
R872 Methylation PhosphoSitePlus
K873 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
T1059 Phosphorylation PhosphoSitePlus
T1068 Phosphorylation PhosphoSitePlus
T1074 Phosphorylation PhosphoSitePlus
K1075 Ubiquitination PhosphoSitePlus
K1082 Ubiquitination PhosphoSitePlus
S1084 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
S1088 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1091 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...18220336
S1093 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1095 Phosphorylation PhosphoSitePlus
T1099 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
T1112 Phosphorylation phospho.ELM 18669648
S1113 Phosphorylation phospho.ELM 18669648
S1123 Phosphorylation phospho.ELM 18669648
Y1179 Phosphorylation PhosphoSitePlus
K1191 Ubiquitination PhosphoSitePlus
S1193 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1196 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18088087, 18220336
C1212 S-Nitrosylation dbSNO 26338901
S1223 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 20068231
T1226 Phosphorylation PhosphoSitePlus
R1229 Methylation PhosphoSitePlus
T1245 Phosphorylation PhosphoSitePlus
Y1264 Phosphorylation PhosphoSitePlus
Y1267 Phosphorylation PhosphoSitePlus
Y1269 Phosphorylation PhosphoSitePlus
T1275 Phosphorylation PhosphoSitePlus
Y1276 Phosphorylation PhosphoSitePlus
K1278 Ubiquitination PhosphoSitePlus
K1282 Ubiquitination PhosphoSitePlus
T1354 Phosphorylation PhosphoSitePlus
S1399 Phosphorylation PhosphoSitePlus
C1423 Methylation IEDB 31844290
Y1517 Phosphorylation PhosphoSitePlus
T1523 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S552 Phosphorylation HPRD 17081983
S555 Phosphorylation HPRD 17081983
S556 Phosphorylation HPRD 17081983
S558 Phosphorylation HPRD 17081983
S559 Phosphorylation HPRD 17525332
S562 Phosphorylation HPRD 17081983
S568 Phosphorylation HPRD 17525332
S572 Phosphorylation HPRD 19651622
S594 Phosphorylation HPRD 19691289
S598 Phosphorylation HPRD 19651622, 18767875
S600 Phosphorylation HPRD 19413330, 17322306, 18491316, ...18212344, 18767875, 19651622, 18669648, 20166139
S609 Phosphorylation HPRD 15302935
S646 Phosphorylation HPRD 19413330, 19664995, 19651622, ...18669648, 20166139, 20068231
S647 Phosphorylation HPRD 19413330, 18669648
S649 Phosphorylation HPRD 19413330, 18669648, 20068231
T651 Phosphorylation HPRD 19413330
T656 Phosphorylation HPRD 18669648
S686 Phosphorylation HPRD 18669648
S688 Phosphorylation HPRD 18669648
S695 Phosphorylation HPRD 18669648
T711 Phosphorylation HPRD 18669648
S713 Phosphorylation HPRD 18669648
S714 Phosphorylation HPRD 18669648
S740 Phosphorylation HPRD 20068231
S741 Phosphorylation HPRD 20068231
S797 Phosphorylation HPRD 17322306, 19413330, 18669648, ...19664994, 18707149
T798 Phosphorylation HPRD 18669648
S1084 Phosphorylation HPRD 20068231
S1088 Phosphorylation HPRD 18669648
S1091 Phosphorylation HPRD 19413330, 17322306, 18491316, ...19664994, 19664995, 19691289, 19651622, 18669648, 20068231
S1093 Phosphorylation HPRD 18669648
T1099 Phosphorylation HPRD 18669648
S1193 Phosphorylation HPRD 19651622, 18669648
S1196 Phosphorylation HPRD 18088087, 20230923, 18077418, ...19664994, 19651622, 20068231
S1223 Phosphorylation HPRD 19651622, 15302935, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T730 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
T1084 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
S1095 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S280 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
S600 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T642 Phosphorylation PhosphoSitePlus
S646 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S647 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S649 Phosphorylation phospho.ELM 18669648
T651 Phosphorylation phospho.ELM 18220336
T656 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S686 Phosphorylation phospho.ELM 18669648
S688 Phosphorylation phospho.ELM 18669648
S695 Phosphorylation phospho.ELM 18669648
T711 Phosphorylation phospho.ELM 18669648
S713 Phosphorylation phospho.ELM 18669648
S714 Phosphorylation phospho.ELM 18669648
S723 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
T730 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S1083 Phosphorylation phospho.ELM 18669648
S1104 Phosphorylation PhosphoSitePlus
T1107 Phosphorylation PhosphoSitePlus
S1108 Phosphorylation PhosphoSitePlus
S1113 Phosphorylation PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus
Y1135 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S214 F214 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K228 T228 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T275 I275 Biomuta DOID:4159 / skin cancer [ cosmic ]
S552 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S562 I562 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S579 C579 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T586 I586 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S633 L633 Biomuta DOID:4159 / skin cancer [ cosmic ]
S636 F636 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T642 R642 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S647 F647 Biomuta DOID:4159 / skin cancer [ cosmic ]
R660 Q660 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S684 I684 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S688 F688 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y697 H697 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S704 F704 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S714 L714 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S760 N760 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1095 M1095 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ]
S1095 Y1095 Biomuta [ cosmic ]
T1099 M1099 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1123 Y1123 Biomuta [ cosmic ]
S1223 Y1223 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1229 Q1229 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1229 P1229 Biomuta [ cosmic ]
K1278 R1278 Biomuta DOID:363 / uterine cancer [ icgc ]