iPTMnet Report for Q7Z406 (MYH14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z406 / MYH14_HUMAN
Protein Name Myosin-14
Gene Name Name: MYH14
Synonyms:KIAA2034;ORFNames:FP17425;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z406
DAG View
PRO Name myosin-14 (human)
Definition A myosin-14 that is encoded in the genome of human.
Short Label hMYH14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z406 (MYH14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation PhosphoSitePlus
R32 Methylation PhosphoSitePlus
S35 O-Glycosylation GlyGen 35008409, 30397120, 34725712, ...26853435, 29351928, 34019948
S35 Phosphorylation PhosphoSitePlus   RLIMS-P 24209856
S42 Phosphorylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus   RLIMS-P 26038232
T51 O-Glycosylation GlyGen 35008409, 30397120, 34725712, ...26853435, 29351928, 34019948
T51 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus   UniProt 24275569
K103 Acetylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
Y154 Phosphorylation PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
K429 Acetylation PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
Y674 Phosphorylation PhosphoSitePlus
K675 Methylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
K706 Acetylation PhosphoSitePlus
T749 Phosphorylation PhosphoSitePlus
Y778 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S783 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
Y843 Phosphorylation PhosphoSitePlus
K845 Acetylation PhosphoSitePlus
K845 Ubiquitination PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
K985 Acetylation PhosphoSitePlus
K985 Ubiquitination PhosphoSitePlus
K999 Acetylation PhosphoSitePlus
K1019 Acetylation PhosphoSitePlus
R1024 Methylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1105 Acetylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
T1175 Phosphorylation PhosphoSitePlus
T1194 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1204 Phosphorylation PhosphoSitePlus
S1328 Phosphorylation PhosphoSitePlus
T1422 Phosphorylation PhosphoSitePlus
T1462 Phosphorylation PhosphoSitePlus
K1469 Acetylation PhosphoSitePlus
K1469 Methylation PhosphoSitePlus
K1469 Ubiquitination PhosphoSitePlus
S1535 Phosphorylation PhosphoSitePlus
S1536 Phosphorylation PhosphoSitePlus
T1573 Phosphorylation PhosphoSitePlus
T1585 Phosphorylation PhosphoSitePlus
T1591 Phosphorylation PhosphoSitePlus
T1630 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation PhosphoSitePlus
K1657 Methylation PhosphoSitePlus
R1665 Methylation PhosphoSitePlus
S1767 Phosphorylation PhosphoSitePlus
S1769 Phosphorylation PhosphoSitePlus
K1799 Acetylation PhosphoSitePlus
I1833 Phosphorylation IntAct 18675813
K1839 Phosphorylation IntAct 18675813
R1854 Phosphorylation IntAct 18675813
L1856 Phosphorylation IntAct 18675813
K1859 Acetylation PhosphoSitePlus
T1940 Phosphorylation PhosphoSitePlus
R1947 Methylation PhosphoSitePlus
T1951 Phosphorylation IntAct   PhosphoSitePlus 18675813
T1953 Phosphorylation IntAct 18675813
S1969 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S1980 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1983 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1989 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
Site PTM Type PTM Enzyme Score Source PMID
T669 Phosphorylation HPRD 20068231
T1585 Phosphorylation HPRD 20068231
T1591 Phosphorylation HPRD 20068231
S1969 Phosphorylation HPRD 19413330
S1989 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
T677 Phosphorylation HPRD 20068231
T1593 Phosphorylation HPRD 20068231
T1599 Phosphorylation HPRD 20068231
S1977 Phosphorylation HPRD 19413330
S1997 Phosphorylation HPRD 19413330


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O14974 (PPP1R12A) S507 Q7Z406 (MYH14) inhibited_association eFIP 31138649


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R32 H32 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S60 L60 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
Y154 C154 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S193 P193 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S220 L220 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K252 T252 Biomuta DOID:3571 / liver cancer [ cosmic ]
K255 T255 Biomuta DOID:4159 / skin cancer [ cosmic ]
K288 M288 Biomuta DOID:184 / bone cancer [ cosmic ]
Y426 D426 Biomuta DOID:1612 / breast cancer [ cosmic ]
K566 T566 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S595 I595 Biomuta DOID:363 / uterine cancer [ cosmic ]
S809 F809 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1024 C1024 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T1194 M1194 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T1204 N1204 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T1591 A1591 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T1599 A1599 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R1665 C1665 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R1854 H1854 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1854 C1854 Biomuta DOID:363 / uterine cancer [ cosmic ]
L1856 F1856 Biomuta DOID:3571 / liver cancer [ cosmic ]
R1947 P1947 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1947 H1947 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1947 C1947 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1951 P1951 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1951 N1951 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1969 F1969 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1977 F1977 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1983 F1983 Biomuta DOID:4159 / skin cancer [ cosmic ]