iPTMnet Report for Q7Z3Z4 (PIWIL4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3Z4 / PIWL4_HUMAN
Protein Name Piwi-like protein 4
Gene Name Name: PIWIL4
Synonyms:HIWI2,PIWI;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3Z4
DAG View
PRO Name piwi-like protein 4 (human)
Definition A piwi-like protein 4 that is encoded in the genome of human.
Short Label hPIWIL4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3Z4 (PIWIL4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
Y339 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
K667 Acetylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S62 C62 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S84 I84 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K676 E676 Biomuta DOID:3571 / liver cancer [ cosmic ]