iPTMnet Report for Q7Z3Z0 (KRT25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3Z0 / K1C25_HUMAN
Protein Name Keratin, type I cytoskeletal 25
Gene Name Name: KRT25
Synonyms:KRT25A;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3Z0
DAG View
PRO Name keratin, type I cytoskeletal 25 (human)
Definition A keratin, type I cytoskeletal 25 that is encoded in the genome of human.
Short Label hKRT25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3Z0 (KRT25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation IEDB 35494241
S433 Phosphorylation HPRD   PhosphoSitePlus 18669648
T437 Phosphorylation HPRD   PhosphoSitePlus 18669648
S442 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T148 A148 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic ]
T209 I209 Biomuta DOID:4159 / skin cancer [ cosmic ]
S442 F442 Biomuta DOID:4159 / skin cancer [ cosmic ]