iPTMnet Report for Q7Z3T8 (ZFYVE16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3T8 / ZFY16_HUMAN
Protein Name Zinc finger FYVE domain-containing protein 16
Gene Name Name: ZFYVE16
Synonyms:KIAA0305;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3T8
DAG View
PRO Name zinc finger FYVE domain-containing protein 16 (human)
Definition A zinc finger FYVE domain-containing protein 16 that is encoded in the genome of human.
Short Label hZFYVE16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3T8 (ZFYVE16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
C41 Methylation IEDB 31844290
Y73 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S167 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S168 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S170 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K205 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
Y219 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
Y221 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S317 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S319 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S446 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K455 Ubiquitination PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
Y541 Phosphorylation PhosphoSitePlus
K548 Ubiquitination PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
Y578 Phosphorylation PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
T616 Phosphorylation PhosphoSitePlus
T625 O-Glycosylation GlyGen 32938750
S626 O-Glycosylation GlyGen 23301498, 30379171, 35132862, ...28657654, 35254053
K627 Ubiquitination PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
Y789 Phosphorylation PhosphoSitePlus
S815 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S845 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T848 Phosphorylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
K865 Ubiquitination PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
T928 Phosphorylation PhosphoSitePlus
T932 Phosphorylation PhosphoSitePlus
S939 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...15144186
S942 Phosphorylation phospho.ELM 18669648
S946 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...15144186
Y998 Phosphorylation IEDB 35494241
K1006 Ubiquitination PhosphoSitePlus
K1011 Ubiquitination PhosphoSitePlus
S1029 Phosphorylation PhosphoSitePlus
T1120 Phosphorylation PhosphoSitePlus
K1147 Ubiquitination PhosphoSitePlus
T1156 Phosphorylation PhosphoSitePlus
Y1201 Phosphorylation PhosphoSitePlus
K1202 Ubiquitination PhosphoSitePlus
Y1204 Phosphorylation PhosphoSitePlus
T1209 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1210 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
K1257 Ubiquitination PhosphoSitePlus
K1336 Ubiquitination PhosphoSitePlus
S1337 Phosphorylation PhosphoSitePlus
K1364 Ubiquitination PhosphoSitePlus
K1367 Ubiquitination PhosphoSitePlus
K1372 Ubiquitination PhosphoSitePlus
Y1381 Phosphorylation PhosphoSitePlus
K1392 Ubiquitination PhosphoSitePlus
K1395 Ubiquitination PhosphoSitePlus
K1413 Ubiquitination PhosphoSitePlus
K1452 Acetylation PhosphoSitePlus
C1463 Methylation IEDB 31844290


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q15797-1 (hSMAD1/iso:1) Interaction PR:Q7Z3T8 (hZFYVE16) PRO 17356069


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 N10 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C41 G41 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y73 C73 Biomuta DOID:1612 / breast cancer [ cosmic ]
S160 F160 Biomuta [ cosmic ]
S167 Y167 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S216 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y219 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S253 Y253 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S305 N305 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S330 F330 Biomuta DOID:4159 / skin cancer [ cosmic ]
K335 N335 Biomuta DOID:363 / uterine cancer [ icgc ]
S348 T348 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S441 I441 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S896 Y896 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S942 Y942 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1120 A1120 Biomuta DOID:263 / kidney cancer [ cosmic ]
T1209 I1209 Biomuta DOID:4362 / cervical cancer [ cosmic ]
K1257 Q1257 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1337 F1337 Biomuta DOID:363 / uterine cancer [ icgc ]
K1392 T1392 Biomuta DOID:3571 / liver cancer [ cosmic ]