iPTMnet Report for Q7Z3K6 (MIER3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3K6 / MIER3_HUMAN
Protein Name Mesoderm induction early response protein 3
Gene Name Name: MIER3
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3K6
DAG View
PRO Name mesoderm induction early response protein 3 (human)
Definition A mesoderm induction early response protein 3 that is encoded in the genome of human.
Short Label hMIER3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3K6 (MIER3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
S53 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332, ...20068231
S114 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
T163 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K299 Acetylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
C452 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation HPRD 19651622, 20068231, 16565220
S53 Phosphorylation HPRD 19651622, 20068231
S156 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 Y16 Biomuta DOID:3571 / liver cancer [ cosmic ]
S17 A17 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y33 C33 Biomuta DOID:263 / kidney cancer [ cosmic ]
T148 I148 Biomuta DOID:363 / uterine cancer [ icgc ]
T163 K163 Biomuta DOID:2021 / placenta cancer [ cosmic ]
S165 G165 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K256 N256 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K306 T306 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K306 N306 Biomuta DOID:9256 / colorectal cancer [ cosmic ]