iPTMnet Report for Q7Z3K3 (POGZ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3K3 / POGZ_HUMAN
Protein Name Pogo transposable element with ZNF domain
Gene Name Name: POGZ
Synonyms:KIAA0461,SUHW5,ZNF280E,ZNF635;ORFNames:Nbla00003;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3K3
DAG View
PRO Name pogo transposable element with ZNF domain (human)
Definition A pogo transposable element with ZNF domain that is encoded in the genome of human.
Short Label hPOGZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3K3 (POGZ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
R183 Methylation PhosphoSitePlus
R213 Methylation IEDB 27503676
T224 O-Glycosylation GlyGen   IEDB 28314751
R238 Methylation PhosphoSitePlus
S239 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T240 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S244 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S246 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T249 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S251 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S251 Phosphorylation PhosphoSitePlus
T252 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S256 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T258 O-Glycosylation GlyGen 32938750
T258 Phosphorylation PhosphoSitePlus
T260 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T262 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T265 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S266 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S274 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S274 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S278 Phosphorylation PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus
T282 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T282 Phosphorylation PhosphoSitePlus
S289 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S292 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S292 Phosphorylation PhosphoSitePlus
S297 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S300 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T303 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T310 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S314 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S314 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S333 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S333 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S340 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S340 Phosphorylation PhosphoSitePlus
S343 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S344 Phosphorylation PhosphoSitePlus
S348 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S352 Phosphorylation PhosphoSitePlus
T361 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S363 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S363 Phosphorylation PhosphoSitePlus   UniProt 23186163
S410 Phosphorylation PhosphoSitePlus
S416 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S419 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S425 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569, 20068231
T429 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T429 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S434 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S434 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus   UniProt 19690332
S445 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
T448 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus   UniProt 24275569
K480 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
C547 Methylation IEDB 31844290
Y647 Phosphorylation PhosphoSitePlus
K666 Ubiquitination PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
T686 Phosphorylation PhosphoSitePlus
T689 Phosphorylation PhosphoSitePlus
T699 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S704 Phosphorylation PhosphoSitePlus
T707 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T707 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T719 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S721 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S746 Phosphorylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
K801 Acetylation PhosphoSitePlus
K801 Sumoylation PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus   UniProt 23186163
K871 Acetylation PhosphoSitePlus
K883 Acetylation PhosphoSitePlus
S949 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
K1030 Ubiquitination PhosphoSitePlus
K1053 Ubiquitination PhosphoSitePlus
T1082 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
K1215 Ubiquitination PhosphoSitePlus
K1223 Ubiquitination PhosphoSitePlus
K1269 Ubiquitination PhosphoSitePlus
S1327 Phosphorylation PhosphoSitePlus
S1338 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...18220336
T1340 Phosphorylation PhosphoSitePlus
S1352 Phosphorylation PhosphoSitePlus
S1360 Phosphorylation PhosphoSitePlus
S1364 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 24275569, ...18220336
S1366 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
S1366 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1367 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
T1368 O-Glycosylation GlyGen 23301498, 28314751, 30620550, ...31492838, 32870666, 35289036, 29249144, 22661428, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 29485866, 29351928, 28657654, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 20068230
T1368 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S1373 Phosphorylation UniProt 29997176
S1374 Phosphorylation UniProt 29997176
T1378 Phosphorylation UniProt 29997176
S1392 Phosphorylation PhosphoSitePlus   UniProt 29997176, 24275569
T1394 Phosphorylation UniProt 29997176
S1396 Phosphorylation UniProt 29997176
Site PTM Type PTM Enzyme Score Source PMID
S251 Phosphorylation HPRD 19413330
T258 Phosphorylation HPRD 19413330
S274 Phosphorylation HPRD 19413330, 18669648
T282 Phosphorylation HPRD 19413330
S333 Phosphorylation HPRD 18669648, 20068231
S416 Phosphorylation HPRD 18669648
S419 Phosphorylation HPRD 19651622, 17081983, 20068231
S425 Phosphorylation HPRD 19413330, 15302935, 19664995, ...18452278, 19651622, 18669648, 20068231, 19691289
T429 Phosphorylation HPRD 18669648
S445 Phosphorylation HPRD 19413330, 18669648
T448 Phosphorylation HPRD 19413330
T492 Phosphorylation HPRD 20068230
S493 Phosphorylation HPRD 20068230
S704 Phosphorylation HPRD 20068231
T707 Phosphorylation HPRD 18669648
S1222 Phosphorylation HPRD 20068231
S1236 Phosphorylation HPRD 20068231
S1259 Phosphorylation HPRD 20068231
S1338 Phosphorylation HPRD 19651622, 18669648, 20068231
S1360 Phosphorylation HPRD 20068231
S1364 Phosphorylation HPRD 19664995, 17081983, 19691289, ...18452278, 19651622, 20068231, 20068230
S1366 Phosphorylation HPRD 20068231
T1368 Phosphorylation HPRD 19664995, 20068231, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S198 Phosphorylation HPRD 19413330
T205 Phosphorylation HPRD 19413330
S221 Phosphorylation HPRD 19413330, 18669648
T229 Phosphorylation HPRD 19413330
S280 Phosphorylation HPRD 18669648, 20068231
S363 Phosphorylation HPRD 18669648
S366 Phosphorylation HPRD 19651622, 17081983, 20068231
S372 Phosphorylation HPRD 19413330, 15302935, 19664995, ...18452278, 19651622, 18669648, 20068231, 19691289
T376 Phosphorylation HPRD 18669648
S392 Phosphorylation HPRD 19413330, 18669648
T395 Phosphorylation HPRD 19413330
T439 Phosphorylation HPRD 20068230
S440 Phosphorylation HPRD 20068230
S651 Phosphorylation HPRD 20068231
T654 Phosphorylation HPRD 18669648
S1169 Phosphorylation HPRD 20068231
S1183 Phosphorylation HPRD 20068231
S1206 Phosphorylation HPRD 20068231
S1285 Phosphorylation HPRD 19651622, 18669648, 20068231
S1307 Phosphorylation HPRD 20068231
S1311 Phosphorylation HPRD 19664995, 17081983, 19691289, ...18452278, 19651622, 20068231, 20068230
S1313 Phosphorylation HPRD 20068231
T1315 Phosphorylation HPRD 19664995, 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y33 C33 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S35 L35 Biomuta DOID:4159 / skin cancer [ cosmic ]
S221 F221 Biomuta DOID:1319 / brain cancer [ icgc ]
R238 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S244 F244 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T262 I262 Biomuta DOID:1319 / brain cancer [ icgc ]
S274 F274 Biomuta DOID:1319 / brain cancer [ icgc ]
T303 A303 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S372 Y372 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S410 F410 Biomuta DOID:4159 / skin cancer [ cosmic ]
S425 Y425 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T439 I439 Biomuta DOID:3571 / liver cancer [ cosmic ]
K480 R480 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T492 I492 Biomuta DOID:3571 / liver cancer [ cosmic ]
S809 P809 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S809 Y809 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S809 F809 Biomuta DOID:363 / uterine cancer [ icgc ]
K871 N871 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ icgc ]
S964 G964 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1307 N1307 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1313 C1313 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1352 P1352 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1360 N1360 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1366 C1366 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1373 * Biomuta DOID:1612 / breast cancer [ cosmic ]