iPTMnet Report for Q7Z3J3 (RGPD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3J3 / RGPD4_HUMAN
Protein Name RanBP2-like and GRIP domain-containing protein 4
Gene Name Name: RGPD4
Synonyms:RGP4;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3J3
DAG View
PRO Name RanBP2-like and GRIP domain-containing protein 4 (human)
Definition A RanBP2-like and GRIP domain-containing protein 4 that is encoded in the genome of human.
Short Label hRGPD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3J3 (RGPD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
Y599 Phosphorylation PhosphoSitePlus
Y606 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
K691 Sumoylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
Y786 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
Y794 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
R891 Methylation PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
K911 Ubiquitination PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S919 O-Glycosylation GlyGen   PhosphoSitePlus 30379171, 35254053, 31492838, ...30620550, 29237092, 20068230
S919 Phosphorylation PhosphoSitePlus
K924 Ubiquitination PhosphoSitePlus
S928 Phosphorylation PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
K994 Methylation PhosphoSitePlus
K994 Ubiquitination PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
K1010 Ubiquitination PhosphoSitePlus
T1017 Phosphorylation PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus
Y1028 Phosphorylation PhosphoSitePlus
T1030 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
K1066 Ubiquitination PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
K1095 Ubiquitination PhosphoSitePlus
K1121 Ubiquitination PhosphoSitePlus
R1128 Methylation PhosphoSitePlus
K1152 Ubiquitination PhosphoSitePlus
T1153 Phosphorylation PhosphoSitePlus
K1161 Ubiquitination PhosphoSitePlus
T1178 Phosphorylation PhosphoSitePlus
K1181 Ubiquitination PhosphoSitePlus
T1185 Phosphorylation PhosphoSitePlus
K1190 Ubiquitination PhosphoSitePlus
K1199 Ubiquitination PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
K1203 Ubiquitination PhosphoSitePlus
K1206 Sumoylation PhosphoSitePlus
K1206 Ubiquitination PhosphoSitePlus
T1210 Phosphorylation PhosphoSitePlus
T1214 Phosphorylation PhosphoSitePlus
K1215 Ubiquitination PhosphoSitePlus
T1217 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
S1262 Phosphorylation PhosphoSitePlus
S1264 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
S1267 Phosphorylation PhosphoSitePlus
S1271 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation P06493 (CDK1) PhosphoSitePlus 18234856
S1298 Phosphorylation PhosphoSitePlus
S1301 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
K1308 Ubiquitination PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
T1314 Phosphorylation PhosphoSitePlus
S1315 Phosphorylation PhosphoSitePlus
T1318 Phosphorylation PhosphoSitePlus
S1322 Phosphorylation PhosphoSitePlus
Y1334 Phosphorylation PhosphoSitePlus
K1369 Ubiquitination PhosphoSitePlus
K1375 Ubiquitination PhosphoSitePlus
K1383 Ubiquitination PhosphoSitePlus
K1391 Ubiquitination PhosphoSitePlus
T1412 Phosphorylation PhosphoSitePlus
S1416 Phosphorylation PhosphoSitePlus
K1421 Ubiquitination PhosphoSitePlus
T1423 Phosphorylation PhosphoSitePlus
K1440 Acetylation PhosphoSitePlus
K1449 Sumoylation PhosphoSitePlus
K1449 Ubiquitination PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
K1459 Ubiquitination PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
T1466 Phosphorylation PhosphoSitePlus
K1470 Ubiquitination PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
T1475 Phosphorylation PhosphoSitePlus
S1479 Phosphorylation PhosphoSitePlus
S1481 Phosphorylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
T1483 Phosphorylation PhosphoSitePlus
S1487 Phosphorylation PhosphoSitePlus
K1491 Ubiquitination PhosphoSitePlus
T1500 Phosphorylation PhosphoSitePlus
T1501 Phosphorylation PhosphoSitePlus
T1505 O-Glycosylation GlyGen 30379171, 31492838, 35254053, ...20068230, 30620550
S1518 O-Glycosylation GlyGen 30379171, 31492838, 35254053, ...20068230, 30620550
T1525 Phosphorylation PhosphoSitePlus
S1526 Phosphorylation PhosphoSitePlus
T1528 Phosphorylation PhosphoSitePlus
T1529 Phosphorylation PhosphoSitePlus
T1530 Phosphorylation PhosphoSitePlus
S1535 Phosphorylation PhosphoSitePlus
K1538 Sumoylation PhosphoSitePlus
K1538 Ubiquitination PhosphoSitePlus
S1543 Phosphorylation PhosphoSitePlus
S1545 Phosphorylation PhosphoSitePlus
K1547 Ubiquitination PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus
K1556 Methylation PhosphoSitePlus
K1579 Methylation PhosphoSitePlus
S1583 Phosphorylation PhosphoSitePlus
T1585 Phosphorylation PhosphoSitePlus
S1591 Phosphorylation PhosphoSitePlus
S1593 Phosphorylation PhosphoSitePlus
K1596 Sumoylation PhosphoSitePlus
K1596 Ubiquitination PhosphoSitePlus
S1605 Phosphorylation PhosphoSitePlus
K1606 Ubiquitination PhosphoSitePlus
S1608 Phosphorylation PhosphoSitePlus
S1614 Phosphorylation PhosphoSitePlus
K1617 Sumoylation PhosphoSitePlus
K1619 Ubiquitination PhosphoSitePlus
Y1634 Phosphorylation PhosphoSitePlus
T1638 Phosphorylation PhosphoSitePlus
K1641 Ubiquitination PhosphoSitePlus
K1652 Ubiquitination PhosphoSitePlus
K1658 Ubiquitination PhosphoSitePlus
S1660 Phosphorylation PhosphoSitePlus
K1664 Ubiquitination PhosphoSitePlus
S1665 Phosphorylation PhosphoSitePlus
K1691 Ubiquitination PhosphoSitePlus
K1724 Ubiquitination PhosphoSitePlus
S1743 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S86 L86 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K106 E106 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K123 Q123 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K133 E133 Biomuta DOID:363 / uterine cancer [ icgc ]
S205 L205 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y606 N606 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K615 N615 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K691 N691 Biomuta DOID:263 / kidney cancer [ cosmic ]
S797 F797 Biomuta DOID:4159 / skin cancer [ cosmic ]
K911 E911 Biomuta DOID:3571 / liver cancer [ cosmic ]
S915 F915 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S919 Y919 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S928 L928 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S978 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S980 L980 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K994 Q994 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1018 A1018 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1086 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1089 Q1089 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1214 S1214 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1224 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1264 N1264 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1264 I1264 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1271 Y1271 Biomuta DOID:363 / uterine cancer [ icgc ]
S1301 I1301 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1308 N1308 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1315 L1315 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1322 F1322 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1322 Y1322 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1334 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1334 H1334 Biomuta DOID:363 / uterine cancer [ icgc ]
K1369 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1375 I1375 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1375 E1375 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K1391 N1391 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1391 R1391 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1416 N1416 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1423 R1423 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1449 N1449 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1456 T1456 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1456 P1456 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1472 Y1472 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1500 I1500 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1528 I1528 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1535 Y1535 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1545 F1545 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1547 I1547 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1556 N1556 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K1579 T1579 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1583 C1583 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1583 R1583 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1593 T1593 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1593 C1593 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1593 A1593 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1614 P1614 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1614 * Biomuta DOID:1319 / brain cancer [ cosmic ]
K1641 R1641 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1660 R1660 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1691 E1691 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]