Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3J2 / VP35L_HUMAN
Protein Name VPS35 endosomal protein sorting factor-like
Gene Name Name: VPS35L
Synonyms:C16orf62;ORFNames:101F10.2;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3J2
DAG View
PRO Name UPF0505 protein C16orf62 (human)
Definition A protein that is a translation product of the C16orf62 gene in human.
Short Label hC16orf62
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3J2 (VPS35L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y32 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163
K309 Ubiquitination PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
K642 Acetylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
Y838 Phosphorylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
Y937 Phosphorylation PhosphoSitePlus
T951 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S71 T71 Biomuta DOID:1324 / lung cancer [ tcga ]
S108 F108 Biomuta DOID:1909 / melanoma [ cosmic ]
Y128 H128 Biomuta DOID:0070003 / blastoma [ cosmic ]
S480 I480 Biomuta DOID:3571 / liver cancer [ icgc ]
S480 N480 Biomuta DOID:0070003 / blastoma [ cosmic ]
K642 Q642 Biomuta DOID:363 / uterine cancer [ tcga ]
S770 L770 Biomuta DOID:363 / uterine cancer [ tcga ]
T951 M951 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T951 R951 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]