iPTMnet Report for Q7Z3J2 (VPS35L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3J2 / VP35L_HUMAN
Protein Name VPS35 endosomal protein-sorting factor-like
Gene Name Name: VPS35L
Synonyms:C16orf62;ORFNames:101F10.2;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3J2
DAG View
PRO Name VPS35 endosomal protein-sorting factor-like (human)
Definition A VPS35 endosomal protein-sorting factor-like that is encoded in the genome of human.
Short Label hVPS35L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3J2 (VPS35L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y32 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
T235 Phosphorylation IEDB 32387766
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163
K309 Ubiquitination PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
K642 Acetylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
Y838 Phosphorylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
K880 Ubiquitination PhosphoSitePlus
K933 Ubiquitination PhosphoSitePlus
Y937 Phosphorylation PhosphoSitePlus
T951 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S60 F60 Biomuta DOID:4159 / skin cancer [ cosmic ]
S71 T71 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S108 F108 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y128 H128 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T131 I131 Biomuta DOID:4159 / skin cancer [ cosmic ]
K309 R309 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S480 N480 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y937 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T951 M951 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T951 R951 Biomuta DOID:1612 / breast cancer [ cosmic ]