iPTMnet Report for Q7Z3G6 (PRICKLE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z3G6 / PRIC2_HUMAN
Protein Name Prickle-like protein 2 precursor
Gene Name Name: PRICKLE2
Organism Homo sapiens (Human)

PRO ID PR:Q7Z3G6
DAG View
PRO Name prickle-like protein 2 (human)
Definition A prickle-like protein 2 that is encoded in the genome of human.
Short Label hPRICKLE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z3G6 (PRICKLE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S66 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
Y472 Phosphorylation PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
T520 O-Glycosylation GlyGen 30379171
T534 Phosphorylation PhosphoSitePlus
T539 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
N551 N-Glycosylation GlyGen 29741879
S571 Phosphorylation PhosphoSitePlus
S588 Phosphorylation PhosphoSitePlus
T592 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
T751 Phosphorylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
Y813 Phosphorylation PhosphoSitePlus
K820 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S319 F319 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S319 Y319 Biomuta DOID:1324 / lung cancer [ cosmic ]
T458 K458 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T534 M534 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S571 F571 Biomuta DOID:4159 / skin cancer [ cosmic ]
S588 R588 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S693 C693 Biomuta DOID:1324 / lung cancer [ cosmic ]
S695 F695 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S731 G731 Biomuta DOID:3571 / liver cancer [ cosmic ]
S753 L753 Biomuta DOID:4606 / bile duct cancer [ cosmic ]