Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z2E3 / APTX_HUMAN
Protein Name Aprataxin
Gene Name Name: APTX
Synonyms:AXA1;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z2E3
DAG View
PRO Name aprataxin (human)
Definition An aprataxin that is encoded in the genome of human.
Short Label hAPTX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z2E3 (APTX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K62 Sumoylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T125 Phosphorylation P05129 (PRKCG) PhosphoSitePlus   Signor 19561170
S132 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S135 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K198 Sumoylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S132 Phosphorylation HPRD 19651622, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S118 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S177 F177 Biomuta DOID:1612 / breast cancer [ tcga ]