iPTMnet Report for Q7RTR2 (NLRC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7RTR2 / NLRC3_HUMAN
Protein Name NLR family CARD domain-containing protein 3
Gene Name Name: NLRC3
Synonyms:NOD3;
Organism Homo sapiens (Human)

PRO ID PR:Q7RTR2
DAG View
PRO Name NLR family CARD domain-containing protein 3 (human)
Definition An NLR family CARD domain-containing protein 3 that is encoded in the genome of human.
Short Label hNLRC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7RTR2 (NLRC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
T751 Phosphorylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
K992 Sumoylation PhosphoSitePlus
K1055 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 P20 Biomuta DOID:1324 / lung cancer [ cosmic ]
K26 E26 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S72 G72 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K670 N670 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K759 N759 Biomuta DOID:363 / uterine cancer [ icgc ]