iPTMnet Report for Q7RTR0 (NLRP9)
Protein Information
| UniProt AC / UniProt ID | Q7RTR0 / NLRP9_HUMAN |
| Protein Name | NACHT, LRR and PYD domains-containing protein 9 |
| Gene Name | Name: NLRP9 Synonyms:NALP9,NOD6,PAN12; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7RTR0 |
| PRO Name | NACHT, LRR and PYD domains-containing protein 9 (human) |
| Definition | A NACHT, LRR and PYD domains-containing protein 9 that is encoded in the genome of human. |
| Short Label | hNLRP9 |
| Category | organism-gene |
Q7RTR0 (NLRP9) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S269 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K303 | Acetylation | score1 | PhosphoSitePlus | |||
| K304 | Acetylation | score1 | PhosphoSitePlus | |||
| K314 | Acetylation | score1 | PhosphoSitePlus | |||
| K316 | Acetylation | score1 | PhosphoSitePlus | |||
| S691 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y693 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S952 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y139 | S139 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S269 | F269 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S269 | Y269 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S270 | Y270 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S270 | F270 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K303 | N303 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ] | |
| S952 | F952 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View