Protein Information

Cytoscape View

UniProt AC / UniProt ID Q7LC44 / ARC_HUMAN
Protein Name Activity-regulated cytoskeleton-associated protein
Gene Name Name: ARC
Organism Homo sapiens (Human)

DAG View
PRO Name activity-regulated cytoskeleton-associated protein (human)
Definition An activity-regulated cytoskeleton-associated protein that is encoded in the genome of human.
Short Label hARC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q7LC44 (ARC) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K55 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
S84 Phosphorylation RLIMS-P 32991626
S170 Phosphorylation RLIMS-P 32991626, 28670266
T175 Phosphorylation RLIMS-P 28670266
S206 Phosphorylation RLIMS-P 28670266
Y274 Phosphorylation PhosphoSitePlus
T380 Phosphorylation RLIMS-P 28670266

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S170 N170 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]