iPTMnet Report for Q7LC44 (ARC)
Protein Information
| UniProt AC / UniProt ID | Q7LC44 / ARC_HUMAN |
| Protein Name | Activity-regulated cytoskeleton-associated protein |
| Gene Name | Name: ARC Synonyms:KIAA0278; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7LC44 |
| PRO Name | activity-regulated cytoskeleton-associated protein (human) |
| Definition | An activity-regulated cytoskeleton-associated protein that is encoded in the genome of human. |
| Short Label | hARC |
| Category | organism-gene |
Q7LC44 (ARC) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S170 | Phosphorylation | score0 | RLIMS-P | 28670266 | ||
| T175 | Phosphorylation | score0 | RLIMS-P | 28670266 | ||
| S206 | Phosphorylation | score0 | RLIMS-P | 28670266 | ||
| K268 | Ubiquitination | score2 | UniProt | 24945773 | ||
| K269 | Ubiquitination | score2 | UniProt | 24945773 | ||
| Y274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T380 | Phosphorylation | score0 | RLIMS-P | 28670266 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S170 | N170 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K269 | N269 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View