iPTMnet Report for Q7L8L6 (FASTKD5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L8L6 / FAKD5_HUMAN
Protein Name FAST kinase domain-containing protein 5, mitochondrial precursor
Gene Name Name: FASTKD5
Synonyms:KIAA1792;
Organism Homo sapiens (Human)

PRO ID PR:Q7L8L6
DAG View
PRO Name FAST kinase domain-containing protein 5, mitochondrial (human)
Definition A FAST kinase domain-containing protein 5, mitochondrial that is encoded in the genome of human.
Short Label hFASTKD5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L8L6 (FASTKD5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
S95 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...16964243
T99 Phosphorylation HPRD   PhosphoSitePlus 18452278
Y166 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
Y451 Phosphorylation PhosphoSitePlus
K507 Acetylation PhosphoSitePlus   UniProt 19608861
T608 Phosphorylation PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
C670 S-Nitrosylation dbSNO 19483679
S676 Phosphorylation PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus
R704 Methylation PhosphoSitePlus
Y730 Phosphorylation PhosphoSitePlus
T761 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K82 N82 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T83 S83 Biomuta DOID:184 / bone cancer [ cosmic ]
Y730 C730 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S762 Y762 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S762 P762 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]