Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L622 / G2E3_HUMAN
Protein Name G2/M phase-specific E3 ubiquitin-protein ligase
Gene Name Name: G2E3
Synonyms:KIAA1333;
Organism Homo sapiens (Human)

PRO ID PR:Q7L622
DAG View
PRO Name G2/M phase-specific E3 ubiquitin-protein ligase (human)
Definition A G2/M phase-specific E3 ubiquitin-protein ligase that is encoded in the genome of human.
Short Label hG2E3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L622 (G2E3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
K31 Acetylation PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K297 I297 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K300 N300 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]