iPTMnet Report for Q7L5Y9 (MAEA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L5Y9 / MAEA_HUMAN
Protein Name E3 ubiquitin-protein transferase MAEA
Gene Name Name: MAEA
Synonyms:EMP;ORFNames:HLC10,PIG5;
Organism Homo sapiens (Human)

PRO ID PR:Q7L5Y9
DAG View
PRO Name E3 ubiquitin-protein transferase MAEA (human)
Definition An E3 ubiquitin-protein transferase MAEA that is encoded in the genome of human.
Short Label hMAEA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L5Y9 (MAEA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y19 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus   UniProt 23186163
K31 Ubiquitination PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K107 Methylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
C302 Methylation IEDB 31844290
K304 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
K323 Sumoylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
C333 Methylation IEDB 31844290
C340 Methylation IEDB 31844290
K375 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K144 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T13 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y19 C19 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K23 R23 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
T28 M28 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K38 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S45 R45 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K121 N121 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
C302 R302 Biomuta DOID:363 / uterine cancer [ icgc ]
S311 N311 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]