Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L591 / DOK3_HUMAN
Protein Name Docking protein 3
Gene Name Name: DOK3
Organism Homo sapiens (Human)

PRO ID PR:Q7L591
DAG View
PRO Name docking protein 3 (human)
Definition A docking protein 3 that is encoded in the genome of human.
Short Label hDOK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L591 (DOK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
R122 Methylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y208 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
T329 Phosphorylation PhosphoSitePlus
S330 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18088087
S333 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
Y381 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
S389 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
Y453 Phosphorylation phospho.ELM   PhosphoSitePlus 16497976
K477 Acetylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y208 Phosphorylation HPRD 16497976
T329 Phosphorylation HPRD 20058876
S330 Phosphorylation HPRD 18088087, 20058876
S333 Phosphorylation HPRD 20058876
T336 Phosphorylation HPRD 20058876
S364 Phosphorylation HPRD 20058876
Y381 Phosphorylation HPRD 16497976
Y432 Phosphorylation HPRD 16497976
Y453 Phosphorylation HPRD 16497976
Site PTM Type PTM Enzyme Score Source PMID
S179 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S194 Y194 Biomuta DOID:10534 / stomach cancer [ tcga ]
S333 F333 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y381 * Biomuta DOID:3571 / liver cancer [ icgc ]
S389 G389 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S407 R407 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y453 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S483 I483 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]