iPTMnet Report for Q7L590 (MCM10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L590 / MCM10_HUMAN
Protein Name Protein MCM10 homolog
Gene Name Name: MCM10
ORFNames:PRO2249;
Organism Homo sapiens (Human)

PRO ID PR:Q7L590
DAG View
PRO Name protein MCM10 homolog (human)
Definition A protein MCM10 that is encoded in the genome of human.
Short Label hMCM10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L590 (MCM10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T85 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 18669648, 19690332
S93 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17525332
S95 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K134 Sumoylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K139 Sumoylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S155 Phosphorylation IEDB   PhosphoSitePlus 27920218
C173 Methylation IEDB 31844290
T192 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
T217 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K313 Sumoylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K362 Sumoylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
K482 Sumoylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
K511 Sumoylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K534 Sumoylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
T541 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
K554 Methylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
K627 Sumoylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
Y641 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
K665 Sumoylation PhosphoSitePlus
K665 Ubiquitination PhosphoSitePlus
K669 Sumoylation PhosphoSitePlus
K675 Sumoylation PhosphoSitePlus
K675 Ubiquitination PhosphoSitePlus
T676 O-Glycosylation GlyGen 29485866, 30379171
K682 Sumoylation PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K695 Sumoylation PhosphoSitePlus
K695 Ubiquitination PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
S706 Phosphorylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K746 Sumoylation PhosphoSitePlus
K746 Ubiquitination PhosphoSitePlus
K762 Sumoylation PhosphoSitePlus
K762 Ubiquitination PhosphoSitePlus
K769 Sumoylation PhosphoSitePlus
K777 Acetylation PhosphoSitePlus
K811 Ubiquitination PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
R827 Methylation PhosphoSitePlus
K831 Ubiquitination PhosphoSitePlus
K854 Sumoylation PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
K869 Sumoylation PhosphoSitePlus
K869 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T85 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
S93 Phosphorylation HPRD 17525332, 18669648, 20068231
T296 Phosphorylation HPRD 18452278
S557 Phosphorylation HPRD 20068231
Y725 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T85 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
S93 Phosphorylation HPRD 17525332, 18669648, 20068231
S143 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T295 Phosphorylation HPRD 18452278
S556 Phosphorylation HPRD 20068231
Y724 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 L26 Biomuta DOID:4159 / skin cancer [ cosmic ]
S54 F54 Biomuta DOID:4159 / skin cancer [ cosmic ]
S150 F150 Biomuta DOID:4159 / skin cancer [ cosmic ]
T217 M217 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S219 F219 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S238 F238 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S238 P238 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K313 E313 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K505 T505 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K520 N520 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T541 S541 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K554 N554 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S556 L556 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S557 L557 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S593 I593 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T625 M625 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S644 P644 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K669 R669 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
T676 I676 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K695 N695 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K695 T695 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S705 F705 Biomuta DOID:1319 / brain cancer [ icgc ]
S706 P706 Biomuta DOID:4159 / skin cancer [ cosmic ]
K733 R733 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K777 N777 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K815 T815 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]