iPTMnet Report for Q7L576 (CYFIP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L576 / CYFP1_HUMAN
Protein Name Cytoplasmic FMR1-interacting protein 1
Gene Name Name: CYFIP1
Synonyms:KIAA0068;
Organism Homo sapiens (Human)

PRO ID PR:Q7L576
DAG View
PRO Name cytoplasmic FMR1-interacting protein 1 (human)
Definition A cytoplasmic FMR1-interacting protein 1 that is encoded in the genome of human.
Short Label hCYFIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L576 (CYFIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K97 Ubiquitination PhosphoSitePlus
Y108 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K110 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K189 Acetylation PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
Y366 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
Y560 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus   UniProt 23186163
N672 N-Glycosylation GlyGen 29741879
C698 Methylation IEDB 31844290
K715 Ubiquitination PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
T769 Phosphorylation PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
C856 Methylation IEDB 31844290
S872 Phosphorylation PhosphoSitePlus
K879 Ubiquitination PhosphoSitePlus
Y887 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
K935 Ubiquitination PhosphoSitePlus
C960 Methylation IEDB 31844290
Y967 Phosphorylation PhosphoSitePlus
Y986 Phosphorylation PhosphoSitePlus
K1038 Ubiquitination PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
K1053 Ubiquitination PhosphoSitePlus
Y1054 Phosphorylation PhosphoSitePlus
T1068 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1083 Ubiquitination PhosphoSitePlus
C1124 Methylation IEDB 31844290
C1139 Methylation IEDB 31844290
C1152 Methylation IEDB 31844290
C1180 Methylation IEDB 31844290
K1188 Ubiquitination PhosphoSitePlus
K1197 Acetylation PhosphoSitePlus
K1197 Ubiquitination PhosphoSitePlus
K1210 Ubiquitination PhosphoSitePlus
K1227 Ubiquitination PhosphoSitePlus
T1234 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1253 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S568 Phosphorylation HPRD 20068231
S576 Phosphorylation HPRD 20068231
T1068 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
S137 Phosphorylation HPRD 20068231
S145 Phosphorylation HPRD 20068231
T637 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y1054 F1054 Biomuta DOID:4362 / cervical cancer [ cosmic ]
K1227 E1227 Biomuta DOID:10534 / stomach cancer [ cosmic ]