iPTMnet Report for Q7L4I2 (RSRC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L4I2 / RSRC2_HUMAN
Protein Name Arginine/serine-rich coiled-coil protein 2
Gene Name Name: RSRC2
Organism Homo sapiens (Human)

PRO ID PR:Q7L4I2
DAG View
PRO Name arginine/serine-rich coiled-coil protein 2 (human)
Definition An arginine/serine-rich coiled-coil protein 2 that is encoded in the genome of human.
Short Label hRSRC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L4I2 (RSRC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692
S4 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T6 Phosphorylation PhosphoSitePlus   UniProt 21406692
T16 Phosphorylation PhosphoSitePlus   UniProt 21406692
S17 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S27 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus   UniProt 18669648, 20068231
S32 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 20068231
S67 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus   UniProt 21406692
S105 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K375 Sumoylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus   UniProt 23186163
S389 Phosphorylation PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K394 Sumoylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
Y407 Phosphorylation PhosphoSitePlus
R418 Methylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
R429 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231
T6 Phosphorylation HPRD 19413330, 19651622, 20068231
T16 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231
S17 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231, 18452278
S27 Phosphorylation HPRD 18767875
S30 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231, 18452278
S32 Phosphorylation HPRD 19413330, 17081983, 16964243, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 18707149, 19415658, 20068231, 18212344
S104 Phosphorylation HPRD 19651622, 20068231
S105 Phosphorylation HPRD 19651622, 20068231
S216 Phosphorylation HPRD 19651622, 20068231
S218 Phosphorylation HPRD 19651622, 20068231
T220 Phosphorylation HPRD 19651622, 18767875, 20068231
S222 Phosphorylation HPRD 19651622, 18767875, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 G4 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S94 F94 Biomuta DOID:4159 / skin cancer [ cosmic ]
S128 Y128 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S145 C145 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S155 L155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S165 L165 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ icgc ]
T220 S220 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S350 C350 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K375 M375 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S389 C389 Biomuta DOID:10283 / prostate cancer [ cosmic ]