iPTMnet Report for Q7L3T8 (PARS2)
Protein Information
| UniProt AC / UniProt ID | Q7L3T8 / SYPM_HUMAN |
| Protein Name | Probable proline--tRNA ligase, mitochondrial precursor |
| Gene Name | Name: PARS2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7L3T8 |
| PRO Name | probable proline--tRNA ligase, mitochondrial (human) |
| Definition | A probable proline--tRNA ligase, mitochondrial that is encoded in the genome of human. |
| Short Label | hPARS2 |
| Category | organism-gene |
Q7L3T8 (PARS2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R55 | Methylation | score1 | PhosphoSitePlus | |||
| Y88 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score1 | IEDB | 31848261 | ||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y430 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R55 | L55 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T163 | M163 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] |
DAG View