iPTMnet Report for Q7L3T8 (PARS2)
Protein Information
UniProt AC / UniProt ID | Q7L3T8 / SYPM_HUMAN |
Protein Name | Probable proline--tRNA ligase, mitochondrial precursor |
Gene Name | Name: PARS2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7L3T8 |
PRO Name | probable proline--tRNA ligase, mitochondrial (human) |
Definition | A probable proline--tRNA ligase, mitochondrial that is encoded in the genome of human. |
Short Label | hPARS2 |
Category | organism-gene |
Q7L3T8 (PARS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R55 | Methylation | score1 | PhosphoSitePlus | |||
Y88 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
T163 | Phosphorylation | score1 | IEDB | 31848261 | ||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y430 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R55 | L55 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T163 | M163 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] |