iPTMnet Report for Q7L2Z9 (CENPQ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L2Z9 / CENPQ_HUMAN
Protein Name Centromere protein Q
Gene Name Name: CENPQ
Synonyms:C6orf139;
Organism Homo sapiens (Human)

PRO ID PR:Q7L2Z9
DAG View
PRO Name centromere protein Q (human)
Definition A centromere protein Q that is encoded in the genome of human.
Short Label hCENPQ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L2Z9 (CENPQ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Acetylation PhosphoSitePlus
S31 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19007248, 20068231
K34 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
S50 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 25395579, 21406692, 19007248, ...20068231
K56 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
T123 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
K130 Ubiquitination PhosphoSitePlus
T135 Phosphorylation P53350 (PLK1) HPRD   PhosphoSitePlus   Signor 18691976, 20068231, 25670858
S138 Phosphorylation P53350 (PLK1) HPRD   PhosphoSitePlus   Signor 25670858, 20068231
S139 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
K149 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
S248 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
S249 Phosphorylation P53350 (PLK1) HPRD   PhosphoSitePlus   Signor   UniProt 25670858, 23186163, 20068231
S253 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
S255 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
T256 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 25670858
S268 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K130 N130 Biomuta DOID:1324 / lung cancer [ cosmic ]
K180 Q180 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T256 I256 Biomuta DOID:2531 / hematologic cancer [ cosmic ]