iPTMnet Report for Q7L2H7 (EIF3M)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L2H7 / EIF3M_HUMAN
Protein Name Eukaryotic translation initiation factor 3 subunit M
Gene Name Name: EIF3M
Synonyms:HFLB5,PCID1;ORFNames:GA17,PNAS-125;
Organism Homo sapiens (Human)

PRO ID PR:Q7L2H7
DAG View
PRO Name eukaryotic translation initiation factor 3 subunit M (human)
Definition A eukaryotic translation initiation factor 3 subunit M that is encoded in the genome of human.
Short Label hEIF3M
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L2H7 (EIF3M) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692, 22814378, ...17322308
S2 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K23 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
C134 Methylation IEDB 31844290
K149 Ubiquitination PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus   UniProt 23186163
K160 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K213 Acetylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K254 Acetylation PhosphoSitePlus   UniProt 19608861
K254 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
C323 Methylation IEDB 31844290
K324 Ubiquitination PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
K344 Methylation PhosphoSitePlus
K344 Sumoylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus   UniProt 23186163
S370 Phosphorylation PhosphoSitePlus
S372 O-Glycosylation GlyGen 23301498, 34725712, 33465208, ...28510447
S372 Phosphorylation PhosphoSitePlus
T374 O-Glycosylation GlyGen 33465208
T374 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 18491316, 19664995
T281 Phosphorylation HPRD 19664994
S337 Phosphorylation HPRD 17924679
Y351 Phosphorylation HPRD 15592455


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K23 T23 Biomuta DOID:363 / uterine cancer [ icgc ]
K89 N89 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K115 N115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
C323 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S335 I335 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S372 P372 Biomuta DOID:9256 / colorectal cancer [ cosmic ]