iPTMnet Report for Q7L190 (DPPA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L190 / DPPA4_HUMAN
Protein Name Developmental pluripotency-associated protein 4
Gene Name Name: DPPA4
Organism Homo sapiens (Human)

PRO ID PR:Q7L190
DAG View
PRO Name developmental pluripotency-associated protein 4 (human)
Definition A developmental pluripotency-associated protein 4 that is encoded in the genome of human.
Short Label hDPPA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L190 (DPPA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 17081983
S25 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
T215 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19664994, 19664995
S221 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19664995
S226 Phosphorylation PhosphoSitePlus   UniProt 21406692
K299 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S25 L25 Biomuta DOID:4159 / skin cancer [ cosmic ]
K47 N47 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S221 F221 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K299 Q299 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K299 E299 Biomuta DOID:10534 / stomach cancer [ cosmic ]