iPTMnet Report for Q7L099 (RUFY3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L099 / RUFY3_HUMAN
Protein Name Protein RUFY3
Gene Name Name: RUFY3
Synonyms:KIAA0871;
Organism Homo sapiens (Human)

PRO ID PR:Q7L099
DAG View
PRO Name protein RUFY3 (human)
Definition A protein RUFY3 that is encoded in the genome of human.
Short Label hRUFY3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L099 (RUFY3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y27 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
C111 Methylation IEDB 31844290
K120 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S456 Phosphorylation PhosphoSitePlus
R499 Methylation PhosphoSitePlus
S506 Phosphorylation HPRD   PhosphoSitePlus 17081983
R510 Methylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 F34 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K120 E120 Biomuta DOID:4159 / skin cancer [ cosmic ]
K181 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K350 I350 Biomuta DOID:1324 / lung cancer [ cosmic ]
K432 N432 Biomuta DOID:1612 / breast cancer [ cosmic ]
R499 K499 Biomuta DOID:4159 / skin cancer [ cosmic ]
S506 N506 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S512 F512 Biomuta DOID:4159 / skin cancer [ cosmic ]