iPTMnet Report for Q7KYR7 (BTN2A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7KYR7 / BT2A1_HUMAN
Protein Name Butyrophilin subfamily 2 member A1 precursor
Gene Name Name: BTN2A1
Synonyms:BT2.1,BTF1;
Organism Homo sapiens (Human)

PRO ID PR:Q7KYR7
DAG View
PRO Name butyrophilin subfamily 2 member A1 (human)
Definition A butyrophilin subfamily 2 member A1 that is encoded in the genome of human.
Short Label hBTN2A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7KYR7 (BTN2A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K57 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
N114 N-Glycosylation GlyGen   UniProt 19349973, 24190977
N120 N-Glycosylation GlyGen   UniProt 24190977, 19349973
K173 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
R439 Methylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T523 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K79 T79 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S107 R107 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K295 N295 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S344 L344 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R439 V439 Biomuta DOID:1319 / brain cancer [ cosmic ]