iPTMnet Report for Q76NI1 (KNDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q76NI1 / KNDC1_HUMAN
Protein Name Kinase non-catalytic C-lobe domain-containing protein 1
Gene Name Name: KNDC1
Synonyms:C10orf23,KIAA1768,RASGEF2,VKIND;ORFNames:hucep-9;
Organism Homo sapiens (Human)

PRO ID PR:Q76NI1
DAG View
PRO Name kinase non-catalytic C-lobe domain-containing protein 1 (human)
Definition A kinase non-catalytic C-lobe domain-containing protein 1 that is encoded in the genome of human.
Short Label hKNDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q76NI1 (KNDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R189 Methylation IEDB 27503676
S190 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
Y922 Phosphorylation PhosphoSitePlus
Y946 Phosphorylation PhosphoSitePlus
S982 Phosphorylation PhosphoSitePlus
S1026 Phosphorylation PhosphoSitePlus
T1145 O-Glycosylation GlyGen 30620550
T1145 Phosphorylation PhosphoSitePlus
S1359 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation PhosphoSitePlus
K1624 Acetylation PhosphoSitePlus
S1700 Phosphorylation PhosphoSitePlus
Y1701 Phosphorylation PhosphoSitePlus
S1710 Phosphorylation PhosphoSitePlus
S1715 Phosphorylation PhosphoSitePlus
T1716 Phosphorylation PhosphoSitePlus
S1721 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S190 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R189 W189 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R189 Q189 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S257 F257 Biomuta DOID:4159 / skin cancer [ cosmic ]
S257 A257 Biomuta DOID:4159 / skin cancer [ cosmic ]
S334 L334 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y946 T946 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1145 A1145 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y1701 C1701 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]