Protein Information

Cytoscape View


UniProt AC / UniProt ID Q76M96 / CCD80_HUMAN
Protein Name Coiled-coil domain-containing protein 80 precursor
Gene Name Name: CCDC80
Synonyms:DRO1,URB;ORFNames:HBE245;
Organism Homo sapiens (Human)

PRO ID PR:Q76M96
DAG View
PRO Name coiled-coil domain-containing protein 80 (human)
Definition A coiled-coil domain-containing protein 80 that is encoded in the genome of human.
Short Label hCCDC80
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q76M96 (CCDC80) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S64 O-Glycosylation PhosphoSitePlus
T65 O-Glycosylation PhosphoSitePlus
T89 O-Glycosylation PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
T323 O-Glycosylation PhosphoSitePlus
K329 Acetylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S409 O-Glycosylation PhosphoSitePlus
S409 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus 23831687
S411 O-Glycosylation PhosphoSitePlus
Y415 O-Glycosylation GlyGen 23584533, 25813380
S418 O-Glycosylation PhosphoSitePlus
S434 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus 23831687
S503 Phosphorylation PhosphoSitePlus
Y506 Phosphorylation PhosphoSitePlus
S513 O-Glycosylation PhosphoSitePlus
T516 O-Glycosylation GlyGen   PhosphoSitePlus 30459171
K545 Sumoylation PhosphoSitePlus
K548 Sumoylation PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K577 Acetylation PhosphoSitePlus
K584 Acetylation PhosphoSitePlus
K586 Acetylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
N667 N-Glycosylation GlyGen 29741879
N835 N-Glycosylation GlyGen 29741879
S877 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S305 R305 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, tcga ]
T323 N323 Biomuta DOID:3571 / liver cancer [ icgc ]
T347 P347 Biomuta DOID:2394 / ovarian cancer [ tcga ]
S513 R513 Biomuta DOID:1324 / lung cancer [ tcga ]
K575 N575 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K584 R584 Biomuta DOID:4362 / cervical cancer [ tcga ]
S618 Y618 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y890 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y890 C890 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S895 L895 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ]