iPTMnet Report for Q76M96 (CCDC80)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q76M96 / CCD80_HUMAN
Protein Name Coiled-coil domain-containing protein 80 precursor
Gene Name Name: CCDC80
Synonyms:DRO1,URB;ORFNames:HBE245;
Organism Homo sapiens (Human)

PRO ID PR:Q76M96
DAG View
PRO Name coiled-coil domain-containing protein 80 (human)
Definition A coiled-coil domain-containing protein 80 that is encoded in the genome of human.
Short Label hCCDC80
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q76M96 (CCDC80) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S64 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T65 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T89 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K232 Acetylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
T323 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K329 Acetylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
T404 O-Glycosylation GlyGen 25813380
S409 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S409 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus 23831687
S411 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
Y415 O-Glycosylation GlyGen 23584533, 25813380
S418 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S434 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus 23831687
S503 Phosphorylation PhosphoSitePlus
Y506 Phosphorylation PhosphoSitePlus
S513 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T516 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S518 O-Glycosylation GlyGen 25813380
K545 Sumoylation PhosphoSitePlus
K548 Sumoylation PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K577 Acetylation PhosphoSitePlus
K584 Acetylation PhosphoSitePlus
K586 Acetylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
T605 O-Glycosylation GlyGen 25813380
T605 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
N667 N-Glycosylation GlyGen 29741879
N835 N-Glycosylation GlyGen 29741879
S877 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S305 R305 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S308 G308 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S411 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S513 R513 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S518 Y518 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K575 N575 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K584 R584 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T605 M605 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S618 Y618 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y890 C890 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S895 L895 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]