iPTMnet Report for Q76G19 (PDZD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q76G19 / PDZD4_HUMAN
Protein Name PDZ domain-containing protein 4
Gene Name Name: PDZD4
Synonyms:KIAA1444,PDZK4,PDZRN4L;
Organism Homo sapiens (Human)

PRO ID PR:Q76G19
DAG View
PRO Name PDZ domain-containing protein 4 (human)
Definition A PDZ domain-containing protein 4 that is encoded in the genome of human.
Short Label hPDZD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q76G19 (PDZD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K24 Ubiquitination PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus   UniProt 21406692
S249 Phosphorylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus   UniProt 21406692
S457 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
T555 Phosphorylation IEDB 35494241
Y581 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
T661 Phosphorylation PhosphoSitePlus
T662 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S236 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S27 F27 Biomuta DOID:4159 / skin cancer [ cosmic ]
S249 L249 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K412 Q412 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S457 F457 Biomuta DOID:4159 / skin cancer [ cosmic ]
S463 W463 Biomuta DOID:1324 / lung cancer [ cosmic ]
T468 N468 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T661 M661 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T662 N662 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T662 I662 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T662 A662 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S701 N701 Biomuta DOID:10534 / stomach cancer [ cosmic ]