iPTMnet Report for Q75V66 (ANO5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q75V66 / ANO5_HUMAN
Protein Name Anoctamin-5
Gene Name Name: ANO5
Synonyms:GDD1,TMEM16E;
Organism Homo sapiens (Human)

PRO ID PR:Q75V66
DAG View
PRO Name anoctamin-5 (human)
Definition An anoctamin-5 that is encoded in the genome of human.
Short Label hANO5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q75V66 (ANO5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T128 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
Y449 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
K897 Acetylation PhosphoSitePlus
K905 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y453 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T454 K454 Biomuta DOID:1324 / lung cancer [ cosmic ]
T454 M454 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S555 N555 Biomuta DOID:1324 / lung cancer [ cosmic ]
K650 Q650 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]