Protein Information

Cytoscape View

UniProt AC / UniProt ID Q71UI9 / H2AV_HUMAN
Protein Name Histone H2A.V
Gene Name Name: H2AFV
Organism Homo sapiens (Human)

DAG View
PRO Name histone H2A.V (human)
Definition A histone H2A.V that is encoded in the genome of human.
Short Label hH2AFV
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q71UI9 (H2AFV) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
K12 Acetylation PhosphoSitePlus
K14 Acetylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
R23 Methylation PhosphoSitePlus
R32 Methylation PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
R92 Methylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
K116 Methylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
K121 Sumoylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 R14 Biomuta DOID:263 / kidney cancer [ tcga ]
R32 H32 Biomuta DOID:363 / uterine cancer [ tcga ]
R92 S92 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S99 Y99 Biomuta DOID:363 / uterine cancer [ icgc, tcga ] DOID:9256 / colorectal cancer [ tcga ]