Protein Information

Cytoscape View


UniProt AC / UniProt ID Q71U36 / TBA1A_HUMAN
Protein Name Tubulin alpha-1A chain
Gene Name Name: TUBA1A
Synonyms:TUBA3;
Organism Homo sapiens (Human)

PRO ID PR:Q71U36
DAG View
PRO Name tubulin alpha-1A chain (human)
Definition A tubulin alpha-1A chain that is encoded in the genome of human.
Short Label hTUBA1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q71U36 (TUBA1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K40 Acetylation PhosphoSitePlus   UniProt 24906155
K40 Methylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
K60 Acetylation PhosphoSitePlus
K60 Sumoylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
T73 Phosphorylation PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Sumoylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
K112 Sumoylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K163 Methylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
K326 Acetylation PhosphoSitePlus
K326 Sumoylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K336 Acetylation PhosphoSitePlus
K336 Sumoylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
T337 Phosphorylation PhosphoSitePlus
K338 Methylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
T349 Phosphorylation PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K352 Sumoylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
K370 Acetylation PhosphoSitePlus
K370 Sumoylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K394 Sumoylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K401 Sumoylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
Y408 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
Y451 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation HPRD 19413330, 18767875, 20058876, ...19415658, 19651622
T51 Phosphorylation HPRD 19651622
S287 Phosphorylation HPRD 20058876
S439 Phosphorylation HPRD 19413330, 19651622, 18669648, ...17081983
Y451 Phosphorylation HPRD 15592455


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S38 R38 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T56 M56 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ] DOID:10534 / stomach cancer [ cosmic ]
Y83 N83 Biomuta DOID:1324 / lung cancer [ tcga ]
K124 * Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K163 N163 Biomuta DOID:1612 / breast cancer [ cosmic ]
K164 T164 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S165 C165 Biomuta DOID:10534 / stomach cancer [ tcga ]
T191 S191 Biomuta DOID:1909 / melanoma [ tcga ]
T193 I193 Biomuta DOID:363 / uterine cancer [ tcga ]
T225 I225 Biomuta DOID:3070 / malignant glioma [ tcga ]
T225 N225 Biomuta DOID:3571 / liver cancer [ icgc ]
S236 F236 Biomuta DOID:363 / uterine cancer [ tcga ]
T257 P257 Biomuta DOID:1909 / melanoma [ cosmic ]
S287 C287 Biomuta DOID:1612 / breast cancer [ tcga ]
S287 T287 Biomuta DOID:3963 / thyroid carcinoma [ icgc ]
S379 N379 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]