iPTMnet Report for Q71SY5 (MED25)
Protein Information
| UniProt AC / UniProt ID | Q71SY5 / MED25_HUMAN |
| Protein Name | Mediator of RNA polymerase II transcription subunit 25 |
| Gene Name | Name: MED25 Synonyms:ACID1,ARC92,PTOV2;ORFNames:TCBAP0758; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q71SY5 |
| PRO Name | mediator of RNA polymerase II transcription subunit 25 (human) |
| Definition | A mediator of RNA polymerase II transcription subunit 25 that is encoded in the genome of human. |
| Short Label | hMED25 |
| Category | organism-gene |
DAG ViewQ71SY5 (MED25) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C84 | Methylation | score1 | IEDB | 31844290 | ||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C429 | Methylation | score1 | IEDB | 31844290 | ||
| K440 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K484 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K545 | Acetylation | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K772 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S184 | F184 | Biomuta | [ cosmic ] | |
| C429 | Y429 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K440 | N440 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
