iPTMnet Report for Q71RC2 (LARP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q71RC2 / LARP4_HUMAN
Protein Name La-related protein 4
Gene Name Name: LARP4
ORFNames:PP13296;
Organism Homo sapiens (Human)

PRO ID PR:Q71RC2
DAG View
PRO Name La-related protein 4 (human)
Definition A La-related protein 4 that is encoded in the genome of human.
Short Label hLARP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q71RC2 (LARP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K11 Ubiquitination PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
C130 Methylation IEDB 31844290
Y141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
R368 Methylation PhosphoSitePlus   UniProt 24129315
K372 Ubiquitination PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
G383 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S404 Phosphorylation PhosphoSitePlus
T418 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...35254053, 34019948, 28510447
T424 Phosphorylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
R443 Methylation PhosphoSitePlus
R445 Methylation PhosphoSitePlus
R450 Methylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
T467 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
R503 Methylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus   UniProt 23186163
C548 Methylation IEDB 31844290
T578 Phosphorylation PhosphoSitePlus   UniProt 24275569
T579 Phosphorylation PhosphoSitePlus   UniProt 24275569
S583 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S586 Phosphorylation PhosphoSitePlus
T587 Phosphorylation PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
T595 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus   UniProt 23186163
C599 Methylation IEDB 31844290
C599 S-Nitrosylation dbSNO 26338901
T607 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus   UniProt 21406692
T649 Phosphorylation PhosphoSitePlus   UniProt 21406692
S660 Phosphorylation PhosphoSitePlus
K667 Acetylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
K674 Methylation PhosphoSitePlus
Y676 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
R680 Methylation PhosphoSitePlus
R686 Methylation PhosphoSitePlus   UniProt 24129315
K691 Methylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
S722 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 15144186, 27920218, ...18669648, 24275569, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S282 Phosphorylation PhosphoSitePlus
S314 Phosphorylation HPRD 18669648
S321 Phosphorylation HPRD 18669648
S419 Phosphorylation HPRD 18669648
S434 Phosphorylation HPRD 20068231
S512 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231
S515 Phosphorylation HPRD 18669648, 20068231
T516 Phosphorylation HPRD 17081983
T517 Phosphorylation HPRD 18669648
S523 Phosphorylation HPRD 18691976, 18669648, 17081983, ...20068231, 19664995
T524 Phosphorylation HPRD 19413330, 18669648, 17081983, ...19664995
S526 Phosphorylation HPRD 19413330, 18669648, 18491316, ...19664995, 20068231
T536 Phosphorylation HPRD 19664995
S572 Phosphorylation HPRD 19413330
S576 Phosphorylation HPRD 19413330, 18669648
T578 Phosphorylation HPRD 19413330
S651 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K11 E11 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S73 C73 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S73 F73 Biomuta DOID:1324 / lung cancer [ cosmic ]
S74 L74 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y141 H141 Biomuta DOID:363 / uterine cancer [ icgc ]
S148 C148 Biomuta DOID:1324 / lung cancer [ cosmic ]
K165 Q165 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S282 L282 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y291 C291 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y291 D291 Biomuta DOID:2998 / testicular cancer [ cosmic ]
R368 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S388 L388 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S388 * Biomuta DOID:1612 / breast cancer [ cosmic ]
R450 K450 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S470 L470 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T474 A474 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S491 L491 Biomuta DOID:4159 / skin cancer [ cosmic ]
R503 M503 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S523 N523 Biomuta DOID:363 / uterine cancer [ icgc ]
S572 Y572 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S576 Y576 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S591 L591 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S594 N594 Biomuta DOID:363 / uterine cancer [ icgc ]
S618 T618 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S618 I618 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S643 Y643 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S647 Y647 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S660 C660 Biomuta DOID:3571 / liver cancer [ cosmic ]
S660 F660 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K667 T667 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R680 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y717 H717 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]