iPTMnet Report for Q71F23 (CENPU)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q71F23 / CENPU_HUMAN
Protein Name Centromere protein U
Gene Name Name: CENPU
Synonyms:ICEN24,KLIP1,MLF1IP,PBIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q71F23
DAG View
PRO Name centromere protein U (human)
Definition A centromere protein U that is encoded in the genome of human.
Short Label hCENPU
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q71F23 (CENPU) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S77 Phosphorylation P53350 (PLK1) PhosphoSitePlus   Signor 17081991
T78 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17081991, 29154753, 17188028, ...31685831
Y81 Phosphorylation PhosphoSitePlus
S94 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S96 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S97 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus   UniProt 23186163
S107 Phosphorylation PhosphoSitePlus
S108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T110 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S111 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S116 Phosphorylation PhosphoSitePlus
S136 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S139 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S141 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T147 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S194 O-Glycosylation GlyGen 30379171
S194 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K197 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
S215 O-Glycosylation GlyGen 30379171
S229 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S232 Phosphorylation PhosphoSitePlus   UniProt 23186163
K244 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K291 Acetylation PhosphoSitePlus
T300 Phosphorylation PhosphoSitePlus
K303 Acetylation PhosphoSitePlus
K303 Methylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K308 Methylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S94 Phosphorylation HPRD 16565220
S96 Phosphorylation HPRD 16565220
T98 Phosphorylation HPRD 20068231
S108 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231
T110 Phosphorylation HPRD 19651622, 18669648
S111 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231
S136 Phosphorylation HPRD 18669648
S139 Phosphorylation HPRD 18669648
S141 Phosphorylation HPRD 18669648, 20068231
T186 Phosphorylation HPRD 18691976
S190 Phosphorylation HPRD 18691976
S194 Phosphorylation HPRD 18691976, 19691289, 20068231
S204 Phosphorylation HPRD 19691289
S229 Phosphorylation HPRD 20068231, 16565220
T231 Phosphorylation HPRD 16565220
S232 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S50 A50 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S94 P94 Biomuta DOID:263 / kidney cancer [ cosmic ]
S96 F96 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S107 G107 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T147 A147 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S206 L206 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S206 A206 Biomuta DOID:9256 / colorectal cancer [ cosmic ]