iPTMnet Report for Q70EL2 (USP45)
Protein Information
| UniProt AC / UniProt ID | Q70EL2 / UBP45_HUMAN |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 45 |
| Gene Name | Name: USP45 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q70EL2 |
| PRO Name | ubiquitin carboxyl-terminal hydrolase 45 (human) |
| Definition | A ubiquitin carboxyl-terminal hydrolase 45 that is encoded in the genome of human. |
| Short Label | hUSP45 |
| Category | organism-gene |
DAG ViewQ70EL2 (USP45) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K391 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S597 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S599 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y666 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S432 | T432 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S474 | G474 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S597 | C597 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
| Y666 | D666 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
