iPTMnet Report for Q70EK9 (USP51)
Protein Information
| UniProt AC / UniProt ID | Q70EK9 / UBP51_HUMAN |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 51 |
| Gene Name | Name: USP51 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q70EK9 |
| PRO Name | ubiquitin carboxyl-terminal hydrolase 51 (human) |
| Definition | A ubiquitin carboxyl-terminal hydrolase 51 that is encoded in the genome of human. |
| Short Label | hUSP51 |
| Category | organism-gene |
DAG ViewQ70EK9 (USP51) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S26 | Phosphorylation | score4 | HPRD PhosphoSitePlus RLIMS-P | 32296027, 19664994 | ||
| K46 | Acetylation | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T359 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C593 | Methylation | score1 | IEDB | 31844290 | ||
| K597 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K604 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T611 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S679 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q8WYQ5 (DGCR8) | S677 | Q70EK9 (USP51) | unknown | eFIP | 34188037 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K46 | R46 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| Y358 | D358 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T359 | I359 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S679 | N679 | Biomuta | DOID:263 / kidney cancer [ cosmic ] |
